Synthesis, characterization and superoxide dismutase activity of bi-copper(II)-bisacetato- μ-phthalicacid[bis(benzyloxy)ethyl]ester

Abstract

A new binuclear copper(II) complex, bridged by the ligand phthalicacid[bis(benzyloxy)ethyl]ester, where each copper(II) is coordinated to one carboxylate (from ligand) and one acetate in square planar mode is reported. The ligand synthesized by the reaction of phthalic anhydride and ethylene glycol, has been characterized by FT-IR, 1 HNMR and LCMS. The binuclear Copper(II) complex has been characterized by UV/visible spectra, FTIR spectra, EPR spectra, ESI-MS spectra, magnetic moment measurement and thermogravimetric analysis. DFT calculation has shown a Z type structure for the complex. Excellent superoxide dismutase activity with IC 50 value 8.6 ×10 -6 M for the complex has been observed. [Figure not available: see fulltext.]