Precocious Puberty in Boys: A Study Based on Five Years of Data from a Single Center in Northern China

Abstract

Objective: To evaluate the clinical features and etiology of precocious puberty (PP) in Chinese boys. Methods: In this study, data from boys who were referred for evaluation of PP from 2015 to 2020 at a tertiary hospital in Northern China were retrospectively analyzed. Results: Eighty-two boys were diagnosed with PP from 2015 to 2020. Sixty-two patients (75.6%) were diagnosed with central PP (CPP), and twenty patients (24.4%) were diagnosed with peripheral PP (PPP). In the CPP group, forty-nine cases were classified as idiopathic CPP, and thirteen patients had pathogenic CPP. The top three causes of PPP were congenital adrenal hyperplasia, germ cell tumors and familial male-limited PP. Conclusion: The etiology of PP in males is diverse. The majority of CPP cases in Chinese boys are idiopathic rather than organic.