Neisseria meningitidis serogroup X in Sub-Saharan Africa

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Abstract

The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub- Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.

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Agnememel, A., Hong, E., Giorgini, D., Nuñez-Samudio, V., Deghmane, A. E., & Taha, M. K. (2016). Neisseria meningitidis serogroup X in Sub-Saharan Africa. Emerging Infectious Diseases, 22(4), 698–702. https://doi.org/10.3201/eid2204.150653

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