Emergence of extended-spectrum β-lactamase (CTX-M-15 and CTX-M-14)-producing nontyphoid Salmonella with reduced susceptibility to ciprofloxacin among food animals and humans in Korea

Abstract

Twenty of 1,279 nontyphoid Salmonella strains isolated from food animals and humans produced CTX-Mtype extended-spectrum β-lactamase. All expressed CTX-M-15, except two which coexpressed CTX-M-14 and TEM-1. Insertion sequence ISEcp1 was identified upstream of blaCTX-M genes. The bla CTX-M-15 and blaCTX-M-14 genes were disseminated by large conjugative IncFIIs and IncI1-Iβ plasmids, respectively. Copyright © 2011, American Society for Microbiology. All Rights Reserved.