Low serum Metrnl levels are associated with increased risk of sarcopenia in the older adults

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Abstract

Aim: To investigate the association of serum Metrnl levels with the risk and severity of sarcopenia in a Chinese population of community-dwelling older adults. Findings: Our present study showed for the first time that serum Metrnl was positively correlated with the components of sarcopenia, including skeletal muscle mass, grip strength, and gait speed. Low serum Metrnl level (< 197.2 pg/mL) was associated with increased risk of sarcopenia in the older adults. Message: Addition of Metrnl to the traditional screening tools may help to facilitate the risk stratification for the patients with sarcopenia.

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Wang, Z. Y., Li, Y. M., Yan, J. J., Wang, Q., Zhao, C., Lu, X., … Gao, W. (2024). Low serum Metrnl levels are associated with increased risk of sarcopenia in the older adults. European Geriatric Medicine, 15(6), 1849–1857. https://doi.org/10.1007/s41999-024-01074-y

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