Synthesis of Quinoxalin-2(1 H)-ones and Hexahydroquinoxalin-2(1 H)-ones via Oxidative Amidation-Heterocycloannulation

Abstract

A metal-catalyst-free synthesis of substituted quinoxalin-2-ones from 2,2-dibromo-1-arylethanone by employing an oxidative amidation-heterocycloannulation protocol is reported. The substrate scope of the reaction has been demonstrated and a possible mechanism for this reaction has also been proposed.