Characterization and simulation of peristaltic micropumps

Abstract

The aim of the work is to find an analytical model of a pneumatic micropump which was integrated into a cell-culture system. This allows the estimation of peak velocities and wall-shear stress influencing the cultured cells in our multi-organ-chip (MOC) with respect to the applied pressure and the geometric properties of the pump. By adjusting those parameters, one can imitate physiological or pathological heart activity. The calculated flow within the MOC was compared to experimental results obtained via the non-invasive micro-PIV method.