THE FORMULATION OF NANOEMULSION SERUM-CONTAINING GOTU KOLA EXTRACT (CENTELLA ASIATICA L. URBAN) AND CHIA SEED OIL (SALVIA HISPANICA) FOR SKIN HYDRATION EFFECT

Abstract

Objective: The aims of this study of nano serum formulation from C. asiatica and chia seed to skin hydration effect. Methods: C. asiatica extraction was macerated by 70% ethanol and evaporated by a rotary evaporator to produce high viscosity of extract yields. Four different formulas were obtained from nanoemulsion serum production with different concentrations of chia seed oil (1%, 2%, 3%, 4%). Two formulas F1 (1% chia seed oil) and F4 (4% chia seed oil) were selected for further clinical testing, which were applied at face skin for 7 d, then were measured using a skin analyzer looking for the best and most effective. Results: Optimation result of extraction method of C. asiatica herb as high as 28.74% extract yields and 3.12% asiaticoside content. The result value of formulation based on the effect of moisturizing/hydration then can be analyzed with the Minitab program using the One-way ANOVA method. The result indicated that the product can increase face skin moistness at 20 respondents, where 13.36% increase from F1 formula and 13.88% increase from F4 formula. Conclusion: The nanoemulsion serum-containing combination of C. asiatica extract and chia seed oil enables to increase in the moisturizing effect on dry skin or normal tend to dry skin.