Therapeutic efficacy of artemether-lumefantrine combination in the treatment of uncomplicated malaria among children under 5 years in 3 ecological zones in Ghana

Abstract

In 2008 artemether-lumefantrine and dihydroartemisinin- piperaquine were added to amodiaquine - artesunate as first line drugs for uncomplicated malaria in Ghana. The introduction of new drugs calls for continuous monitoring of these drugs to provide timely information on trends of their efficacy and safety to enhance timely evidence-based decision making by the National Malaria Control Pro- gramme. In this regard, we monitored the therapeutic effi- cacy of artemether - lumefantrine from September 2010 to April 2011 in 4 sentinel sites representing the 3 main eco- logical zones of the country.