Antiphospholipid syndrome

Abstract

Antiphospholipid antibodies were found mainly in the serums of patients with systemic lupus erythematosus (prevalence of 20-50 %). The combination of antiphospholipid antibodies with thrombosis, spontaneous abortion and thrombocytopenia received the name of antiphospholipid syndrome. For the determination of antiphospholipid antibodies, three main tests are used-biological, inhibition of blood coagulation and immunoanalysis. The exact mechanism by which antiphospholipid antibodies induce clinical manifestations of antiphospholipid syndrome is still unknown. The diagnosis of Antiphospholipid syndrome is based on both clinical and serological criteria.