Antimicrobial activity of substituted azoles and their nucleosides

Abstract

Four new 2'-deoxynucleosides of benzimidazole derivatives were prepared. Antimicrobial activity of many indazole, benzotriazole, benzimidazole derivatives and their nucleosides were tested by the agar diffusion method. Among the investigated compounds, dinitro- and trifluoromethyl-substituted benzimidazoles and their nucleosides were the most potent.