The Impact of Infant Bacille Calmette-Guérin Vaccination on the Immunogenicity of Other Vaccines: A Randomized Exploratory Study

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Abstract

The effect of the Bacille Calmette-Guerin (BCG) vaccine on the immunogenicity of separately administered serogroup C meningococcal vaccine and other vaccinations was examined in 28 infants randomized to receive BCG at age ≤7 days, at 3 months or after study completion. Immunogenicity of the serogroup C meningococcal vaccine and other routine vaccines might be improved when BCG is administered in early infancy.

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Maytum, A., Porter, D., De Whalley, P., Thompson, A., Plested, E., Kerridge, S., … Pollard, A. J. (2024). The Impact of Infant Bacille Calmette-Guérin Vaccination on the Immunogenicity of Other Vaccines: A Randomized Exploratory Study. Pediatric Infectious Disease Journal, 43(8), 809–812. https://doi.org/10.1097/INF.0000000000004373

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