Investigation of fetal cardiac function using tissue doppler imaging in fetuses compromised by growth restriction

Abstract

Objectives: The primary aim of this study was to evaluate fetal cardiac systolic and diastolic function using the tissue Doppler technique in pregnancies with complications of fetal growth restriction (FGR) and to examine the relationship between FGR with umbilical artery Doppler parameters and fetal cardiac function in complicated pregnancies. Material and methods: This study included 30 pregnant women with FGR complications and 46 pregnant women without FGR complications. Both groups were at 24–34 gestational weeks. Fetal cardiac examination was performed using pulsed Doppler and tissue Doppler imaging (TDI) in all pregnancies. In the analysis of myocardial tissue by tissue Doppler, the tracing obtained from the junction of the tricuspid valve annulus with the right ventricle was recorded by measuring the duration of the isovolumetric contraction wave (IVC), ejection time (ET), and isovolumetric relaxation time (IVR). Furthermore, we calculated the myocardial performance index (MPI) and then measured and recorded the early diastolic annular rate. Results: Based on the TDI studies, the mean IVC and IVR values were significantly longer and the ET values were significantly shorter in the study group than those in the control group. The study group also had significantly longer MPI measurements. Conclusions: Because TDI is a considerably more sensitive method than cardiac sonographic evaluation using pulsed Doppler, tissue Doppler parameters facilitate the detection of cardiac dysfunction at a relatively early stage. In addition, TDI and myocardial evaluation in fetuses with FGR can be noninvasively performed in clinical practice.