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Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals

Antimicrobial Agents and Chemotherapy (2012) 56(4) 2125-2128
DOI: 10.1128/AAC.05315-11
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Abstract

Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is a point mutant form of OXA-48. Both carbapenemase genes were located on IncL/M-type conjugative plasmids. Insertion sequence IS1999 (truncated or not by IS1R) was located upstream of the bla OXA-48 and bla OXA-162 genes in all of the isolates. Pulsed-field gel electrophoresis typing indicated the clonal transmission of an OXA-48-producing Klebsiella pneumoniae strain in two hospitals. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

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CITATION STYLE

APA

Pfeifer, Y., Schlatterer, K., Engelmann, E., Schiller, R. A., Frangenberg, H. R., Stiewe, D., … Poirel, L. (2012). Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals. Antimicrobial Agents and Chemotherapy, 56(4), 2125–2128. https://doi.org/10.1128/AAC.05315-11

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