Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals

77Citations
Citations of this article
123Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is a point mutant form of OXA-48. Both carbapenemase genes were located on IncL/M-type conjugative plasmids. Insertion sequence IS1999 (truncated or not by IS1R) was located upstream of the bla OXA-48 and bla OXA-162 genes in all of the isolates. Pulsed-field gel electrophoresis typing indicated the clonal transmission of an OXA-48-producing Klebsiella pneumoniae strain in two hospitals. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

Cite

CITATION STYLE

APA

Pfeifer, Y., Schlatterer, K., Engelmann, E., Schiller, R. A., Frangenberg, H. R., Stiewe, D., … Poirel, L. (2012). Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals. Antimicrobial Agents and Chemotherapy, 56(4), 2125–2128. https://doi.org/10.1128/AAC.05315-11

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free