Carbohydrate Components of Extraneuronal Gangliosides from Bovine and Human Spleen, and Bovine Kidney

Abstract

The gangliosides from bovine spleen and kidney as well as human spleen, were extracted from the tissues. The carbohydrate‐portion of the gangliosides was characterized. Bovine spleen gangliosides and those isolated from bovine kidney contained the same sialo‐oligosaccharide moieties. Eleven different ganglosides from the bovine tissues and five gangliosides from human spleen were identified. They are derived from lactose, ganglio‐N‐triose, ganglio‐N‐tetraose, lacto‐N‐neotetraose or lacto‐N‐tetraose and differ in their content of sialic acid. Gangliosides from human tissue contain N‐acetyl‐neuraminic acid only. The sialic acid of the gangliosides from bovine spleen consist of either N‐acetyl‐neuraminic acid, N‐glycolyl‐neuraminic acid or both. Copyright © 1970, Wiley Blackwell. All rights reserved