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Zn mediated regioselective Barbier reaction of propargylic bromides in THF/aq. NH4Cl solution

Molecules (2001) 6(12) 964-968
DOI: 10.3390/61200964
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Abstract

The reaction of substituted and unsubstituted propargylic bromides with butanal in presence of zinc power in THF/saturated aqueous NH4Cl solution gave corresponding allenic and propargylic alcohols with high selectivity.

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Jõgi, A., & Mäeorg, U. (2001). Zn mediated regioselective Barbier reaction of propargylic bromides in THF/aq. NH4Cl solution. Molecules, 6(12), 964–968. https://doi.org/10.3390/61200964

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