Abstract
An allergen-stimulating cytokine, interleukin-13 (IL-13), plays a significant role in allergic inflammation. Benzyl isothiocyanate (BITC), derived from several cruciferous vegetables, significantly suppressed the IL-13 expression in the calcium iono-phore-stimulated human basophilic KU812 cells. Down-regulation of phosphorylated mitogenactivated protein kinases as well as nuclear transcriptional factors might be involved in the underlying mechanism.
Author supplied keywords
Cite
CITATION STYLE
Tang, Y., Abe, N., Yoshimoto, M., Zhu, B., Murata, Y., & Nakamura, Y. (2015). Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells. Bioscience, Biotechnology and Biochemistry, 79(1), 159–163. https://doi.org/10.1080/09168451.2014.963503
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
