Primary intracranial leptomeningeal melanomatosis

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Abstract

Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures.

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Kim, D. H., Choi, C. Y., Lee, C. H., & Joo, M. (2015). Primary intracranial leptomeningeal melanomatosis. Journal of Korean Neurosurgical Society, 58(6), 554–556. https://doi.org/10.3340/jkns.2015.58.6.554

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