Recent Advances in Cell-Mediated Drug Delivery Systems for Nanomedicine and Imaging

Abstract

Therapeutic delivery systems have been developed and used to carry therapeutic agents such as drugs, proteins, and genes to targeted disease sites to enhance drug efficacy and reduce toxicity. However, off-target and immunogenicity remain the major challenges for delivery systems. To overcome these problems, various cell-mediated delivery platforms have been explored to specifically and efficiently deliver therapeutic agents into the disease sites owing to their unique properties. This chapter summarizes the recent advances in cell-mediated drug delivery systems and their application. The cell types and functions for drug delivery, responsive delivery, and their application in disease treatment and imaging as well as clinical applications have been discussed.