On the wobble GoU and related pairs

Abstract

The wobble GoU pairs have been implicated in several biological processes where molecules play a key role. We review the geometrical and conformational properties of wobble GoU pairs on the basis of available crystal structures of RNA at high resolution. The similarities with the wobble A+oC pairs and UoU pairs are illustrated, while the differences with the recently discovered bifurcated G·U pairs are contrasted.