N-(2,6-Dimethoxypyridin-3-yl)-9-methyl-9H-carbazole-3-sulfonamide

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Abstract

In the title compound, C20H19N3O 4S, a novel tubulin ligand active against human cancer, the dihedral angle between the pyridine ring and the carbazole ring system is 42.87 (10)°. In the crystal, the molecules are held together by N-H⋯O and C-H⋯O hydrogen bonds into layers, which are assembled into a three-dimensional network via π-π stacking interactions between inversion-related pyridine rings, with centroid-centroid distances of 3.5101 (12) Å.

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Shan, G., Li, Z., Hu, L., Jiang, J., & Liu, Z. (2013). N-(2,6-Dimethoxypyridin-3-yl)-9-methyl-9H-carbazole-3-sulfonamide. Acta Crystallographica Section E: Structure Reports Online, 69(4). https://doi.org/10.1107/S1600536813007460

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