Assessment of Multidrug Resistance Tuberclosis Treatment Outcome in St. Petre’s Tuberclosis Specialized Hospital, Addis Ababa, Ethiopia

Abstract

The purpose of this study is to assess the treatment outcome of MDR-TB among patients who are treated in St. Peter’s TB Specialized Hospital from January 1, 2009 to December 31, 2010. A periodic retrospective cross sectional study was conducted on MDR-TB patient who were followed up to check their treatment out come. The study was utilized quantitative method for data collection by using patient registration book from MDR-TB clinic retrospectively. Using data collecting format, cure rate, failure rate, death rate, card number, sex, address, and co-morbid illness was be collected. The association with the patient treatment outcome was assessed using SPSS version 15 for window using chi-square and odds ratio and Epi info for data entry. In this study the treatment outcome was measured by cure rate, death rate, failure rate and default rate. Base on this study that was done in St. Peter’s TB specialized hospital from January 1, 2009 to December 31, 2010 cohort study, out of 166 MDR-TB patients, the treatment completion and cure rate was 7(4.2%). Regarding to sex more female 6(7.1%) of the treated patients were cured than male 1(1.23%) from the total females and males patients respectively. While 143(83.5%) were still on treatment, 1(0.6%) patient was defaulted from treatment for more than two months and the outcome was not traced. Treatment failure was not reported in this study. This finding indicates that from the study population, no treatment failure and one treatment interruption (default) was observed. In conclusion patients in this cross sectional study were found in good follow up and DOTS program. On the other hand the cure rate 7(4.2%) of this study showed that encouraging treatment outcome was obtained from the MDR-TB treatment plan. The result that was obtained from this study showed that the majority of MDR-TB patients in this retrospective study were found still on treatment.