Optical Activity and Absolute Configuration of 2,3 :6,7-Dibenzobicyclo [3.3.1]nona-2,6-diene Derivatives

Abstract

2,3 : 6,7-Dibenzobicyclo[3.3.1]nona-2,6-diene-4,8-diol was synthesized and resolved via (−)-menthoxyacetate. Several kinds of optically active derivatives with the same absolute configuration were prepared from the (−)-diol and their chiroptical properties were recorded. The absolute configuration of this series of compounds was determined to be 1R, 5R by a chemical correlation with (R)-(−)-3-phenylbutanoic acid via (−)-1,3-diphenylglutaric acid and (−)-2,4-diphenylpentane.