Activation of allylic C-F bonds: Palladium-catalyzed allylic amimation of 3,3-difluoropropenes

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Abstract

(Chemical Equation Present) Lose one, keep one! A wide range of cyclic and acyclic ß-aminofluoroalkenes are prepared by the title reaction. The key fluorinated palladium π-allyl intermediate is generated using a catalytic allylic C-F bond activation. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA,.

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Pigeon, X., Bergeron, M., Barabé, F., Dubé, P., Frost, H. N., & Paquin, J. F. (2010). Activation of allylic C-F bonds: Palladium-catalyzed allylic amimation of 3,3-difluoropropenes. Angewandte Chemie - International Edition, 49(6), 1123–1127. https://doi.org/10.1002/anie.200904747

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