Abstract
A simple, highly efficient three-component reaction involving acid chlorides, terminal alkynes, and ethyl 2-amino-1H-indole-3-carboxylates, for the synthesis of highly diversified pyrimido[1,2-a]indoles has been described. The salient feature of the reaction involves sequential Sonogashira and [3+3] cyclocondensation reactions. © 2011 Elsevier Ltd. All rights reserved.
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Gupta, S., Sharma, S. K., Mandadapu, A. K., Gauniyal, H. M., & Kundu, B. (2011). Three-component tandem reaction involving acid chlorides, terminal alkynes, and ethyl 2-amino-1H-indole-3-carboxylates: Synthesis of highly diversified pyrimido[1,2-a]indoles via sequential Sonogashira and [3+3] cyclocondensation reactions. Tetrahedron Letters, 52(33), 4288–4291. https://doi.org/10.1016/j.tetlet.2011.06.021
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