Competing and simultaneous click reactions at the interface and in solution

Abstract

The kinetics of two simultaneous "click" reactions (thiol-maleimide addition and thiol-disulfide exchange) were investigated by NMR spectroscopy in homogeneous solution and at the oil/water interface of an inverse miniemulsion. For the polyaddition/-condensation of difunctional reagents it was found that the thiol-disulfide exchange is faster than the thiol-maleimide reaction. The addition of a basic catalyst influences the copolymerization behavior of the competitive "click" reactions.