Platelet-rich plasma as an effective alternative approach for improving endometrial receptivity-a clinical retrospective study

Abstract

Objective: The aim of the present case series was to describe our experience with the use of PRP on patients with refractory thin endometria. Methods: This retrospective analysis included 24 IVF cycles in which patients presenting different infertility factors received intrauterine PRP infusion prior to embryo transfer. Outcomes of interest were: clinical and ongoing pregnancies, miscarriages, and births. Results: 54% of the cycles in which PRP was employed resulted in ongoing gestation or birth; 12.5% of the cycles ended in miscarriages. Conclusion: Our data suggest that PRP improves in-trauterine receptivity to embryo implantation, regardless of whether the endometrium reached the appropriate growth for embryo transfer.