Gram-negative prosthetic joint infections: risk factors and outcome of treatment

Abstract

Little information is available regarding the demographic characteristics and outcomes of patients with prosthetic joint infection (PJI) resulting from gram-negative (GN) organisms, compared with patients with PJI resulting from gram-positive (GP) organisms. Methods. We performed a retrospective cohort analysis of all cases of PJI that were treated at our institution during the period from 2000 through 2006. Results. GN microorganisms were involved in 53 (15%) of 346 first-time episodes of PJI, and Pseudomonas aeruginosa was the most commonly isolated pathogen (21 [40%] of the 53 episodes). Patients with GN PJI were older (median age, 68 vs. 59 years; P