Journal Article

Acute Encephalopathy Associated with Influenza A Infection in Adults

  • Lee N
  • Wong C
  • Chan P
  • et al.
Emerging Infectious Diseases (2010) 16(1) 139-142
DOI: 10.3201/eid1601.090077
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Abstract

We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.

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Lee, N., Wong, C. K., Chan, P. K. S., Lindegardh, N., White, N. J., Hayden, F. G., … Hui, D. S. C. (2010). Acute Encephalopathy Associated with Influenza A Infection in Adults. Emerging Infectious Diseases, 16(1), 139–142. https://doi.org/10.3201/eid1601.090077

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