Airway Pressure Release Ventilation as a Rescue Therapy in Pediatric Acute Respiratory Distress Syndrome

9Citations
Citations of this article
33Readers
Mendeley users who have this article in their library.

Abstract

Objectives: To describe experience with airway pressure release ventilation (APRV) in children with severe acute respiratory distress syndrome (ARDS) refractory to conventional low tidal volume ventilation. Methods: This retrospective observational study was performed in an 11-bed, level 3 pediatric intensive care unit. Evaluation was made of 30 pediatric patients receiving airway pressure release ventilation as rescue therapy for severe ARDS. Results: Patients were switched to APRV on an average 3.2 ± 2.6 d following intubation. When changed from conventional mechanical ventilation (CMV) to APRV, there was an expected increase in the SpO2/FiO2 ratio (165.1 ± 13.6 vs. 131.7 ± 10.2; p = 0.035). Mean peak inspiratory pressure was significantly lower during APRV (25.4 ± 1.26 vs. 29.8 ± 0.60, p < 0.001) compared to CMV prior to APRV but mean airway pressure (Paw) was significantly higher during APRV (19.1 ± 0.9 vs. 15.3 ± 1.3, p < 0.001). Hospital mortality in this study group was 16.6%. Conclusions: The results of this study support the hypothesis that APRV may offer potential clinical advantages for ventilatory management and may be considered as an alternative rescue mechanical ventilation mode in pediatric ARDS patients refractory to conventional ventilation.

References Powered by Scopus

Long-term effects of spontaneous breathing during ventilatory support in patients with acute lung injury

507Citations
N/AReaders
Get full text

Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure

403Citations
N/AReaders
Get full text

Pediatric acute respiratory distress syndrome: Definition, incidence, and epidemiology: Proceedings from the Pediatric Acute Lung Injury Consensus Conference

325Citations
N/AReaders
Get full text

Cited by Powered by Scopus

A narrative review of advanced ventilator modes in the pediatric intensive care unit

11Citations
N/AReaders
Get full text

Does airway pressure release ventilation offer new hope for treating acute respiratory distress syndrome?

6Citations
N/AReaders
Get full text

Random Forest-Based Prediction of Acute Respiratory Distress Syndrome in Patients Undergoing Cardiac Surgery

3Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Yener, N., & Üdürgücü, M. (2020). Airway Pressure Release Ventilation as a Rescue Therapy in Pediatric Acute Respiratory Distress Syndrome. Indian Journal of Pediatrics, 87(11), 905–909. https://doi.org/10.1007/s12098-020-03235-w

Readers over time

‘20‘21‘22‘23‘24‘25036912

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 4

50%

Professor / Associate Prof. 2

25%

Lecturer / Post doc 1

13%

Researcher 1

13%

Readers' Discipline

Tooltip

Medicine and Dentistry 9

64%

Nursing and Health Professions 2

14%

Business, Management and Accounting 2

14%

Decision Sciences 1

7%

Article Metrics

Tooltip
Mentions
News Mentions: 1

Save time finding and organizing research with Mendeley

Sign up for free
0