Therapeutic potential of phosphoinositide 3-kinase inhibitors in rheumatoid arthritis

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Abstract

Activation of PI3K is a key step of intracellular signaling involved in many cellular functions. PI3K inhibitors have shown anti-rheumatic effects on arthritis model in mice. PI3K is a potential therapeutic target of rheumatoid arthritis. © 2007, The Japan Society for Clinical Immunology. All rights reserved.

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Tamura, N., & Haruta, K. (2007). Therapeutic potential of phosphoinositide 3-kinase inhibitors in rheumatoid arthritis. Japanese Journal of Clinical Immunology, 30(5), 369–374. https://doi.org/10.2177/jsci.30.369

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