Destruction of Strongyloides venezuelensis infective larvae by fungi Duddingtonia fagrans, Arthrobotrys robusta and Monacrosporium sinense

Abstract

Introduction: Strongyloides venezuelensis has been used as a model for studying human strongyloidosis. Methods: Tis study aimed to compare the ability of predatory nematophagous fungi Duddingtonia fagrans (AC001), Arthrobotrys robusta (I-31) and Monacrosporium sinense (SF53) and on infective larvae (L3) of Strongyloides venezuelensis in laboratory conditions on 2% water-agar medium. Results: At the end of the experiment, the percentage reductions of Strongyloides venezuelensi L3 were: 93% (AC001), 77.2% (I-31) and 65.2% (SF53). Conclusions: Te nematophagous fungi were able to capture and destroy the L3 in vitro and can be used as biological controllers of Strongyloides venezuelensi.