Organ on a chip (Kidney)

Abstract

Organ on a chip (OOC) is called an artificial organ, and it is a multi-channel the purpose of the chip is to absence in vivo the chip consists of both digital and analog part digital part mainly dedicated to the communication protocol, it also includes power management with clock switches; silicon is a promising material due to its reliable and required features for making porous silicon membrane. OOC deals with the precise bio-MEMS. Porous membrane is used in so many applications mostly in Biomes’, lab on chip and mems. This paper explains the effect of pressure through the silicon membrane based on the deflection different thickness of membranes and pore shapes in various levels of pressure applied on silicon membrane. 10nm thin silicon membrane was studied to be far superior to the 25nm silicon thin membrane being able to automatically survive the applied force up to 7-33kpa (55mhg).