Application of the ATC/DDD Method to Evaluate Captopril and Nifedipine Usage in Bluluk-Lamongan Regency Healthcare Service

Abstract

Hypertension occurs when the systolic blood pressure is more than 140 mmHg and the diastolic is more than 90 mmHg. Hypertension might cause damage to the body’s organs directly or indirectly. This study aimed to analyze the use of the drugs Captopril and Nifedipin at the Bluluk Health Center, Bluluk District, Lamongan using the ATC/DDD method. This was an observational study with a retrospective descriptive design. Data collection was carried out using quantitative methods, more specifically the ATC/DDD method. The results of DDD/1000 inhabitants/day of the drug Nifedipine 10 mg in 2020 were highest in January, namely 0.98 mg, and the lowest was 0.17 mg in October with an average of 0.46 mg. For DDD/1000 inhabitants/day, the drug Captopril 12.5 mg in 2020, the highest in January was 3.6 mg and the lowest in May was 0.4 mg with an average of 1.6 mg. For DDD/1000 inhabitants/day, the drug Captopril 25 mg in 2020 was the highest in August at 7.6 mg and the lowest in April was 1.2 mg with an average of 3.7 mg. The DDD value of Nifedipine 10 mg was less than the World Health Organization value of DDD Nifedipine, which is 30 mg. The DDD value of Captopril (12.5 mg and 25 mg) was also less than the World Health Organization DDD of 50 mg, so it can be concluded that the use of Nifedipine 10 mg and Captopril (12.5 mg and 25 mg) is still controlled. Keywords: Captopril, Nifedipine, ATC/DDD, hypertension, healthcare service