Abstract
High‐molecular‐mass protein was isolated from chicken heart muscle. The apparent molecular mass of a single polypeptide chain is similar to that of chicken gizzard filamin: 250–270 kDa. The protein interacts with antibodies against chicken gizzard filamin and induces F‐actin gelation in a concentration‐dependent manner. Immunofluorescent staining of cardiomyocytes and chicken heart sections with antifilamin antibody demonstrates two types of filamin localization: (a) filamin was located on the sarcomete border in the periphery of the Z‐disk; (b) filamin was found in intercalated disks between cardiomyocytes. Copyright © 1986, Wiley Blackwell. All rights reserved
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CITATION STYLE
KOTELIANSKY, V. E., GLUKHOVA, M. A., GNEUSHEV, G. N., SAMUEL, J. ‐L, & RAPPAPORT, L. (1986). Isolation and localization of filamin in heart muscle. European Journal of Biochemistry, 156(3), 619–623. https://doi.org/10.1111/j.1432-1033.1986.tb09622.x
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