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Antimicrobial activity of novel furanonaphthoquinone analogs

Antimicrobial Agents and Chemotherapy (1998) 42(3) 700-702
DOI: 10.1128/aac.42.3.700
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Abstract

Analogs of furanonaphthoquinone (FNQ) from Tecoma ipe Mart had MICs ranging from 1.56 to 25 μg/ml against gram-positive bacteria. FNQ showed significantly lower MICs against methicillin-resistant Staphylococcus aureus than against methicillin-sensitive S. aureus. FNQ inhibited Helicobacter pylori with an MIC of 0.1 μg/ml. Fungi, including pathogenic species, were sensitive to FNQ with MICs similar to those of amphotericin B.

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Nagata, K., Hirai, K. I., Koyama, J., Wada, Y., & Tamura, T. (1998). Antimicrobial activity of novel furanonaphthoquinone analogs. Antimicrobial Agents and Chemotherapy, 42(3), 700–702. https://doi.org/10.1128/aac.42.3.700

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