A convenient and efficient one-step method for the synthesis of dicompartmental ligands with hexa- and tetradentate coordination sites

Abstract

A convenient and more efficient method for the preparation of 1,6-bis(2-pyridyl)-2,5-bis(2hydroxy-3-formyl-5-methyl benzyl)-2,5-diazahexane, L1H2 and 1,7-bis(2-pyridyl)-2,6-bis(2-hydroxy-3-formyl- 5methyl benzyl)-2,6-diazaheptane, L2H2 are described. The ligands were prepared by reaction of two moles of 3(chloromethyl)-2-hydroxy-5- methyl benzaldehyde with a mole of N,N'-bis(2-pyridyl)dopamine in THF at ambient conditions in high yield (75-80%). © 2010 Chemical Society of Ethiopia.