Visible-Light-Mediated 5-exo-dig Cyclizations of Amidyl Radicals

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Abstract

A visible-light-mediated synthesis of 5-methylene-pyrrolidinones is reported. This constitutes to the first reported example of a 5-exo-dig hydroamination reaction involving a nitrogen-centered radical.

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Reina, D. F., Dauncey, E. M., Morcillo, S. P., Svejstrup, T. D., Popescu, M. V., Douglas, J. J., … Leonori, D. (2017). Visible-Light-Mediated 5-exo-dig Cyclizations of Amidyl Radicals. European Journal of Organic Chemistry, 2017(15), 2108–2111. https://doi.org/10.1002/ejoc.201601607

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