New pregnane glycosides from Caralluma negevensis

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Abstract

Twenty new pregnane glycosides were isolated from the whole plant of Caralluma negevensis. Their structures were elucidated by extensive spectroscopic methods including 1D-(1H, 13C, 13C DEPT, TOCSY, ROESY) and 2D-NMR experiments (DQF-COSY, HSQC, HMBC, HOHAHA) as well as ESI-MS analysis. Pregnane glycosides were tested for their cytotoxic and genotoxic activity. © 2002 Elsevier Science Ltd. All rights reserved.

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Braca, A., Bader, A., Morelli, I., Scarpato, R., Turchi, G., Pizza, C., & De Tommasi, N. (2002). New pregnane glycosides from Caralluma negevensis. Tetrahedron, 58(29), 5837–5848. https://doi.org/10.1016/S0040-4020(02)00563-X

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