The widespread occurrence of cryptococcosis mainly in immunocompromised patients and the side effects of available drugs which are effective against this mycosis have led investigators to search for new antimycotic agents. Caryocar brasiliensis derived compounds were investigated against Cryptococcus neoformans using the agar dilution method. Based on MIC values, the best results were obtained with a concentration of ≤250μg/mL of cuticular waxes of the Caryocar brasiliensis leaf collected during the dry period (170.8mm of precipitation) which inhibited the growth of 91.3% (21/23) Cryptococcus neoformans isolates.
CITATION STYLE
Passos, X. S., Da Costa Santos, S., Ferri, P. H., De Fátima Lisboa Fernandes, O., De Freitas Paula, T., Ferreira Garcia, A. C., & Rodrigues Silva, M. do R. (2002). Antifungal activity of Caryocar brasiliensis (caryocaraceae) against Cryptococcus neoformans. Revista Da Sociedade Brasileira de Medicina Tropical, 35(6), 623–627. https://doi.org/10.1590/s0037-86822002000600013
Mendeley helps you to discover research relevant for your work.