Cerebral X-linked adrenoleukodystrophy: Follow-up with magnetic resonance imaging

Abstract

Objective: To report a case of childhood cerebral X-linked adrenoleukodystrophy (X-ADL), emphasizing the magnetic resonance imaging (MRI) findings at initial evaluation and at the follow-up. Case report: Five year-old boy, who was asymptomatic, presented with diagnosis of X-ADL for MRI evaluation. The initial brain MRI showed a focal area of enhancement at the splenium of the corpus calosum. One year later, the follow-up MRI showed a pro g ression of the corpus calosus lesion, as well as other lesions in the parietal and occipital lobes. Conclusion: The brain MRI follow-up of patients with X-ADL is important to show the progression of the lesions.