1,3-Dipolar cycloaddition approach to novel dispiro[pyrazolidine-4,3'- pyrrolizidine-2',3"-indoline]-2",3,5-triones

Abstract

A simple and convenient 1,3-dipolar cycloaddition of non-stabilised azomethine ylides derived from isatins and L-proline, in a variety of different solvents, to (Z)-4-arylidene-1-phenylpyrazolidine-3,5-diones as dipolarophiles afforded a series of novel dispiro[pyrazolidine- 4,3'-pyrrolizidine-2',3"-indoline]-2",3,5-triones regioselectively and in good yields.