Enhanced fetal MRI diagnosis of esophageal atresia using super-resolution slice-to-volume reconstruction

Abstract

Background: Prenatal diagnosis of esophageal atresia remains challenging, with indirect signs such as polyhydramnios, a small or absent stomach bubble, and a dilated upper esophageal pouch often inconsistently present. Only 10-40% of EA cases are diagnosed prenatally. Fetal MRI can overcome ultrasound limitations; however, constraints like motion can hinder evaluation of the esophagus. Methods: Super-resolution imaging with slice-to-volume reconstruction (SVR) is one approach that can improve image quality. This technique generates high-resolution 3D images from standard fetal MRI slices to enhance diagnostic accuracy. Aim: We present the application of super-resolution imaging with SVR to accurately diagnose EA and assess the presence or absence tracheoesophageal fistulas. Conclusion: This technique demonstrates significant potential for accurately delineating the relevant surgical anatomy, which can improve surgical planning.