An Eco-Friendly and Efficient Photoinduced Coupling of Alkenes and Alkynes with H-Phosphinates and Other P(O)H Derivatives Under Free-Radical Conditions

Abstract

An efficient method for the synthesis of organophosphorus compounds from alkenes or alkynes and P(O)H compounds under neutral and free-radical conditions was developed. The reaction takes place without solvent, at room temperature, open to the air, using just 0.1 equiv. of 2,2-dimethoxy-2-phenylacetophenone (DPAP) as photoinitiator, and with the unsaturated compound and P(O)H derivative in an equimolar ratio. The reaction can also proceed under irradiation by sunlight, which makes this approach respectful to the environment.