Pattern of adverse drug reactions in a tertiary care teaching hospital: A cross-sectional study

Abstract

Objective: The aim of this study was to carry out adverse drug reactions (ADRs) monitoring in various departments of a tertiary care teaching hospital. Methods: A cross-sectional study was conducted on ADRs reported in the hospital from December 2012 to May 2013 after obtaining Institutional Ethics Committee approval. Results: A total of 40 ADRs were reported, 47.50% were males and 52.50% were females. The female adult population was 45%. The majority of ADRs were due to antimicrobial agents especially beta-lactam antibiotics (42.5%) followed by NSAIDs (7.50%). A maximum number of patients (75%) were reported with dermatological manifestations. The department of medicine reported the highest number of ADRs (37.5%). As per Naranjo’s probability scale, 62.5% reports were assessed as probable. 62.5% reports were documented as mild according to Modified Hartwig’s criteria for severity assessment. Conclusion: This study was done to sensitize the practicing physicians on the importance of adverse drug monitoring and reporting.