GENTAMICIN: MYTHS AND TRUTHS

Abstract

Gentamicin belongs to the group of antimicrobial agents, aminoglycosides. It is the prototype member of this group of antimicrobial agents that is utilized to treat various bacterial infections, mostly those caused by Gram negative bacteria. This is due to its irreversible binding to the 30S component of the ribosome. But the use of aminoglycosides and thus Gentamicin is limited owing to its profound adverse effects on the ear & the kidney. But proper calculation of the dosage can limit these side effects and prove to be an effective antimicrobial agent.