Immunogenicity of pneumococcal vaccine in heart transplant recipients

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Abstract

To assess the immunogenicity of pneumococcal vaccine in recipients of heart transplants, we immunized 35 long-term transplantation survivors with pneumococcal vaccine and measured the pre- and postvaccination IgG antibody titers to 5 representative vaccine capsular polysaccharides. Responses of heart transplant recipients to pneumococcal vaccine antigens were generally suppressed.

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Blumberg, E. A., Brozena, S. C., Stutman, P., Wood, D., Phan, H. M., & Musher, D. M. (2001). Immunogenicity of pneumococcal vaccine in heart transplant recipients. Clinical Infectious Diseases, 32(2), 307–310. https://doi.org/10.1086/318482

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