Radiographic quantification of left atrial size in dogs with myxomatous mitral valve disease

Abstract

Background: In the absence of echocardiography, identification of cardiomegaly via thoracic radiography is a necessary criterion for classification of disease severity in dogs with myxomatous mitral valve disease (MMVD). Objective: Modified-vertebral left atrial size (M-VLAS) facilitates objective radiographic assessment of the left atrium (LA) in 2 dimensions and identifies LA enlargement more accurately than existing methods. Animals: Sixty-four dogs with various stages of MMVD and 6 control healthy dogs. Methods: Retrospective case–control study. Medical records were searched for dogs with varying severity of MMVD. Modified-vertebral left atrial size, vertebral left atrial size (VLAS), vertebral heart size (VHS), and radiographic left atrial dimension (RLAD) were measured from thoracic radiographs and compared with echocardiographically derived measurements. Results: Positive correlation to LA/Ao was identified for M-VLAS (r = 0.77, P