Physical performance of elderly adults in association with thigh tissue composition: A cross-sectional study

Abstract

[Purpose] Literature has revealed age-related changes in body regional tissues in the form of reduced muscle size and increased adipose tissue. There is also a decline in the performance of physical function with aging. The aim of this study is to examine the partial and part correlations between physical performance and thigh tissue composition among elderly adults. [Subjects and Methods] Twenty-two elderly participants enrolled in this cross-sectional study. Mid-thigh CT images were used to determine the cross-sectional area of the muscular and adipose tissues. Principal component score of physical function was calculated from 5 performance based physical function tests using principal component analysis. Partial and part correlation statistics were used to explore the association between physical performance and tissue composition. [Results] There were significant, moderate negative partial and part associations between the principal component score and cross-sectional area of thigh muscles, quadriceps muscle and quadriceps normal density muscle. Significant, moderate positive partial and part correlations were found between intramuscular adipose tissue and the principal component score. [Conclusion] Elderly adults’ performance of physical function is associated with regional tissue composition.