Growth temperature reversibly modulates the virulence of Legionella pneumophila

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Abstract

In chemostat culture, the virulence of two strains of Legionella pneumophila was shown to be significantly (P < 0.05) reduced when the culture temperature was lowered from 37 to 24°C. This modulation was reversed by returning the temperature to 37°C, which resulted in a statistically significant (P < 0.05) increase in virulence.

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Mauchline, W. S., James, B. W., Fitzgeorge, R. B., Dennis, P. J., & Keevil, C. W. (1994). Growth temperature reversibly modulates the virulence of Legionella pneumophila. Infection and Immunity. https://doi.org/10.1128/iai.62.7.2995-2997.1994

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